PFS3AIO all the way (for me)
BUT, it´s good to have one small "standard" partition
for software who doesn't like PFS.
I only found AMBERMOON and Soul Crystal.
(i tested hundreds of Games´n Demos
)
For Soul Crystal i use the WHDLoad version (that fixes that)
and Ambermoon is installed on a FFS THALION: partition
* Ambermoon would corrupt save/loading when on PFS3AIO
* Soul Crystal would have corrupt intro graphics on PFS3AIO
But other than that, PFS3AIO is the best for me