It crashes my machine on launch, using SmartCrash I can see the problem is an 'Illegal Instruction'. If I try and run it with snoopdos going even SmartCrash can't help me, instant machine death.
I tried with a minimal startup - booted with no startup sequence, ran setpatch, and then ran the game - same deal, reboot and an 8000 0004.
I'd blame my machine, but every other game is working fine