I remember that anime, they show it on italy, and was kinda below average,both as animation and plot; it is interesting to remember that, in the same subject, we also had the american Bravestarr (that had some good characters beside the filmation skin) and - some years later, the excellent Trigun.
now, THAT would be an interesting game, starring Vash the Stampede and the mythical Nicholas Wolfwood carrying its own cross-machine gun!
[inspired indeed by Django and its gatling in the coffin i suppose]