Hey!
Using my new copy of Sixth Sense Investigations Talkie CD-ROM in WinUAE R8, the menu screen where the menu is for doing various things like look, talk you get the idea. Anyway the screen is offset. The curser is 5cm away from where the action is supposed to be.
Observe in this screenshot you can clearly see the mouse is placed in a black spot on the menu but the action itself is on the ZieHe option.
Is there a fix? If not it would be a good thing to look into for the next version if WinUAE.