Yes I know, this is amiga community, but eventually all of us moved to PC or Mac. This topic should be simillar to mame tread where you suggest PC games that you think are worth checking or that have 'classic' status.
Also if game was released on Amiga, write which version you find better.
Here is my start of the list:
UFO - Enemy Unknown (aka X-Com)
I liked amiga version of this game enough that this was first PC game that I got. I still prefer Amiga version even I did not find much difference...
Total Annihilation
One of most underrated PC titles. Not sure why as it looks and plays much better then any RTS of its time.
... (just like matrix - to be contued
)