A great pre-configured workbench:
http://eab.abime.net/amiga-scene/621...-winuae-3.html
Also, newer versions of WinUAE have the ability to run borderless, fullscreen windowed mode. Using this feature, and a program on Aminet called Winlaunch, you can have native window apps launched from the Amiga side for the few things where the Amiga lacks.
http://aminet.net/package/util/misc/winlaunch
Amikit had some use for winlaunch in some of their newer distros. Having it launch Google Chrome or some document conversion software could be useful.