I was Amiga and Sega Genesis owner at the same time and imho those attempts to bring "Sonic killer" to Amiga resulted in rather mediocre games that didn't match the Sonic in terms of speed, graphics detail, level design. What's funny according to documentary film Yuji Naka had to slow down game's speed a bit before final release!
What was 16 bit Sega's advantage over Amiga? Better skilled dev teams & huge budgets? Direct access to storage (cartridge)? Why wasn't plain vanilla A500 able to do sth like that?