Originally Posted by gilgamesh
The prices for memory imploded and processors are dirt cheap. Most costly would be the production of chipsets and assembly.
If you don't like FPGAs, then you could make it into a conventional system on a chip with hardwired logic. But that's probably not what you had in mind.
Amiga ASIC based system like C64DTV? Very possible and for about $40-50 for motherboard. Case and keyboard=expensive.
JE was far enough on this to replace OCS chipset in an A500 motherboard, and she said it was a lot less complex than replicating all the quirks in a C64 VIC-II and SID chip to be honest.