One game I don't miss playing on floppy is King's Quest VI. Once I entered an area, switched disks, and it took so long to load I forgot which direction I came from and went back to the previous screen, more disk-switching. Of course then I went the way I wanted in the first place, switching disks again.
Of course I had a hard drive, but you had to make some sacrifices when you only had a 20MB hard drive. KQ6 was ten disks!