The SAM Flex
is a next generation AmigaOS 4
system which runs the new Workbench 4.1. It does not run on any other OS including Linux. It has been written natively to run on the SAM Flex
You can run a lot of 68k apps and some system friendly games through the integrated Petunia system that automatically runs in the background of AmigaOS 4. The hardware unfriendly games can be run on E-UAE for the AmigaOS 4.
There is a post on Amiga.org right now where a user has uploaded YouTube videos of ImageFX (68K) , TVPaint (68K) and Lightwave (68K) running on a SAM Flex: