Might thrash the disk but I dont know if it might thrash the disk drive! Then again, there was this demo that made the diskdrive "sing" a song, and I heard from aa very good source (ie Overdoc, floppydisk meister
), that this fucked up the floppydrive.
Talking about hardware-killing software, there was a little Basic program on the PET machines that made the tape unit catch flames! It consisted of turning on and off the motor very fast... it literally burned the motor!
By the way, I dont think changing color depths to wrong values would burn a videocard, I suppose teh virus forces the videocard on an unsupported frequencey. That could fuck up the card/monitor.