Depends. It's like some apps are meant to be run in certain platforms. Much in the way like games when they got ported from their original platforms, used to suffer badly.
Much like Deluxe Paint IIe on the PC. Nothing it is compared to Amiga versions of DP (even the old ones)
I have seen a Mac running ProTools with the Protools board (dunno which one, I forgot!), and it was a corker. Much better than a PC of "similar" characteristics.