There are soooo many. Here's a couple for now:
Geoff Crammond's F1GP
One of the first Amiga games that I bought. The guitar, drums, fast tempo and visuals wind you up to play. Showing F1 car stats, building up a car and using the BBC TV F1 theme tune (can't remember what it's called), I was desperate to get into my virtual car.
Ran this under emulation a few weeks back and it is still impressive (so is the 'game over' tune - but that's OT!)
Bart vs the Space Mutants
Shame about the game.
Simple slideshow; but great graphics and funky music
I think I'll be coming back to this topic...