I still have somewhere original disk, and IIRC I didn't have problems running the game with sound (at the time I had crappy SB compatible card) under Win95. (DOS)
IIRC game starts exactly where Flashback ends, but after many tries I failed to make it even trough first level. Duke Nukem 3D, C&C and Warcraft might be some of the reasons I didn't give it much chance later.
If you have problems running it under DOSBox, try PSX version. (got that somewhere as well
I might give it a try later this week.
ERM, there is this web site that we are not supposed to mention, that has original F2B CD image...