Okay, I'll try to be shorter than my last rant on this....
There have been the odd nice 2D games in the past few years since the demise of the 16bit machines, but they're still few & far between.
For example Oddworld Abe's Odysee,(though this is on PSX, haven't played it on PC.)
Although I'm in a minority, I also really like the original "Blood Omen Legacy of Kain". I loved playing it on PSX, but when I tried to track it down, I could only locate the PC version-a tad jerky with scrolling, but otherwise okay.
I enjoyed Starcraft & Curse of Monkey Island on PC though they're old examples too.