Is the C64 DTV doing well? If it is, then after a few iterations the people behind it might be willing to do a proper "sequel", and maybe Nick Tinker's design/expertise could be a good starting point for them if he's willing to play along. An Amiga-in-a-joystick done in the style of the DTV would very likey sell pretty well.
This is of course providing that the costs of the licenses won't kill the idea outright. OS 3.1 is (absurdly) not free after more than a decade, and the rights to all of the Psygnosis back-catalog is held by Sony.