[Mr Creosote]

One of my favourite game themes Here are a few additions to what's already been mentioned:

221B Baker Street
Case of the Cautious Condor
Deja Vu (and its sequel)
In the Dead of Night
Mean Streets
Murder Makes Strange Deadfellows
Murder on the Mississippi
Sherlock Holmes: Another Bow
Sherlock Holmes: Consulting Detective (two sequels)
Sixth Sense Investigations
The Detective Game
The Last Express