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Yes, "Fastest Possible" and "JIT" enabled are the most important settings for best speed, but also drag the "CPU Idle" slider to the leftmost position and for the UAE graphics board you can enable "Multithreaded".
Btw, on my Mini-PC with N4100 CPU, 2*2 MB cache, it seems to be a little faster to use only 8 MB JIT cache instead of the maximal 16 MB.
On the Windows side make sure that all the Amiga partitions or directories are added to the exclude list of the Windows Defender real-time protection or other malware scanners.
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