As long as it doesn't cause further fragmentation then I don't see any issue. But it's important that the person playing on their Classic Amiga and the person playing it on the windows/mac/lin executable both have quality experiences.
Maybe if a toolkit/IDE is to be developed, this could be an export option?
-> Export to ADF
-> Export to ADF loaded in DF* of emulated 68000 (Win/Mac/Lin) ...