CDTV Issue
 

..

The ones I had trouble with were as follows:

... Defender of the Crown [CDTV]: solution was to covert the image to .BIN & .CUE.
... Murder Makes Strange Deadfollows CDTV: solution was to set "NTSC".
... Xenon 2: Megablast [CDTV]: solution was to add a ",delay" at the end of the "cdimage0=" line or set "NTSC".

What are the games you're having issues with Amigajay?

I could also test / try things ;)

I just tried "Sherlock Holmes on a Disc - Illustrated Sherlock Holmes" with the image that I found on the EAB File Server.

It worked without issue in WinUAE 4.2.1 using a CDTV Quickstart.

Using 2M chip RAM should also "fix" those that only normally work if CD is inserted when CDTV title screen is shown. (Same happens with real CDTV).

CDTV not even a full 1mb of Ram :(